The Diagnostic Value of C-Reactive Protein Titer in Suspected Acute Appendicitis

Abstract

Acute appendicitis is one of the most common causes of acute abdominal pain requiring surgical intervention. Despite its frequency, diagnosing appendicitis remains challenging, especially in atypical presentations or in early stages of the disease. Misdiagnosis can lead to unnecessary surgeries or delayed treatment with serious complications. While clinical examination and imaging are key components in diagnosis, laboratory biomarkers such as C-reactive protein titer (CRP T) have emerged as valuable supportive tools. Aim of this study is to assess accuracy of C-reactive protein titer in acute appendicitis. The prospective study will be conducted on patient have symptoms and sign of acute appendicitis with high CRP titer presenting to general surgery of alwahda hospital. This study are in strong agreement with the data collected through the prospective observational method. The data were gathered from 24 patients presenting with clinical features suggestive of acute appendicitis, that included demographic details, symptoms, CRP titers, and final through operative findings or follow-up evaluation. The consistency observed between elevated CRP levels (≥ 2.5 mg/dL) and confirmed cases of acute appendicitis (18 out of 18) validates the reliability and integrity of the data collection process. Additionally, the identification of 3 false negatives (CRP < 2.5 mg/dL but diagnosis confirmed) highlights the sensitivity of the dataset to variations, reinforcing the importance of comprehensive clinical assessment. This prospective observational study suggests that CRP titer, in conjunction with clinical features (especially abdominal pain, fever, leukocytosis), While not definitive alone.