A Review of the Phytochemical Composition and Therapeutic Uses of Artemisia spp.
DOI:
https://doi.org/10.58987/2fmb5792Keywords:
Artemisia, Phytochemicals, Therapeutic uses, Natural drugsAbstract
Species of the genus Artemisia are rich sources of biologically active phytochemicals, including terpenoids, flavonoids, phenolic acids, and essential oils, contributing to their diverse therapeutic applications. These species have been extensively studied and demonstrated a wide range of pharmacological activities such as antimalarial (e.g., artemisinin), antioxidant (e.g., quercetin), antimicrobial (e.g., camphor), and anticancer (e.g., artemisinin and its derivatives) effects, highlighting their importance in both traditional and modern medicine. Artemisinin, a key sesquiterpene lactone, has revolutionized malaria treatment globally. However, research on Artemisia faces challenges regarding standardization of extraction methods (such as ethanol, methanol, and aqueous extracts being common) and analytical protocols, as well as the need for comprehensive clinical trials to validate efficacy and safety. This narrative review provides a comprehensive summary of the phytochemical composition and therapeutic uses of various Artemisia spp., emphasizing major bioactive compounds and potential mechanisms of action. The findings highlight the significant potential of Artemisia spp. as sources for novel natural drug development, calling for further clinical studies and standardization efforts to ensure the quality and efficacy of herbal products.
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